/Domain[0 1] Secure .gov websites use HTTPS What is Scottie Pippen's Twitter account? Because symptoms of the condition overlap with other related connective tissue disorders, it is vitally important that your physicians be knowledgeable about Marfan syndrome. such as contact sports, intense physical activity, and weightlifting, can put strain on the heart or joints or make it more likely for your eye lens to move out of place. Marfan syndrome affects the cardiovascular system by making the aorta (an artery that begins at the heart and is the largest in the human body) wider and more fragile. In Marfan syndrome approximately 25% of cases are due to a spontaneous mutation, and neither parent has the condition. A person with Marfan syndrome has a 50 percent chance of passing along this condition to each child. Most people with Marfan's have the whole thing, but its not uncommon for someone to have part of the symptoms. There has long been a connection between a Marfan syndrome (or other connective tissue) diagnosis and anxiety and depression. It includes our Emergency Alert Card which you can download and carry in your wallet. To help prepare you for these situations, we recommend that you complete our Emergency Preparedness Kit, which we created specifically for people with Marfan syndrome and related conditions. Less often, people have problems in blood vessels other than the aorta. Masks are required inside all of our care facilities. Severe scoliosis, breastbone abnormalities, or eye problems like retinal detachment or cataracts may also require surgery. This website was funded in part by an education grant from the Chu and Chan Foundation | Website by: HeartSpark Design | Photography by: Tim Joyce Photography and Rick Guidotti, Kyphoscoliotic Ehlers-Danlos Syndrome (kEDS), Learn More About How to Manage Marfan Syndrome. The affected gene is FBN1. These may include: You can also take steps to prepare for an emergency. About 3 out of 4 people with Marfan syndrome inherit it, meaning they get the genetic mutation from a parent who has it. Many different mutations within the FBN1 gene can cause Marfan syndrome, so no single blood test can diagnose the condition. Both the cardiovascular and skeletal systems are affected by this condition. The series of CT scans and DNA tests confirm he was a victim of Marfan syndrome. Most people who have Marfan syndromegetit from their parents. /Domain[0 1] For most people with Marfan syndrome, the problem starts in the segment of the aorta closest to the heart. Noteworthy, Isaiah Austin had suffered a retinal detachment at age 11, which was ascribed to trauma related to a baseball injury. Create your free account or Sign in to continue. Ophthalmologists may prescribe glasses or contact lenses if you have vision problems due to Marfan syndrome or another CTD. , it is not safe for you to become pregnant. This means you might fix an aneurysm in the upper aorta with a Dacron graft, but the downstream, or lower part of the aorta, will need additional grafts over time. "A kind heart and beautiful soul gone way too soon. Larry Greenemeier is the associate editor of technology for Scientific American, covering a variety of tech-related topics, including biotech, computers, military tech, nanotech and robots. Scoliosis CareScoliosis may need to be addressed with physical therapy, bracing, or other treatments. Still, you can have the gene but not get the whole problemin other words you would have a low penetrance. One quarter of cases may be the result of a spontaneous gene mutation. However, there are some added risks during pregnancy and delivery. Born on September 25, 1965 in Hamburg, Arkansas, Scottie Pippen is the youngest of the 12 children of Ethel and Preston Pippen. 4 0 obj The only symptoms a person may have are forceful heartbeats and shortness of breath during light activity. Sometimes, the pain is less severe, but people still have the feeling that something is very wrong. If a dissection is suspected, a person needs immediate medical attention and should go to a hospital emergency department right away. The genetic defect of fibrillin-1 leads to an increase in the production of another protein, transforming growth factor beta, or TGF-B. Marfan's syndrome results from a gene mutation that leads the body to overproduce a particular proteincalled transforming growth factor beta (TGF-) causing problems in connective tissue . Because connective tissue disorders are hereditary, your doctor will take time to understand your family history. They also should not take part in competitive sports that make the heart work harder. But in terms of Will Perdue, Steve Kerr and the young man, Scott Burrell, that was heartbreaking [to watch]. Evaluation in a specialized center with cardiology and medical genetics expertise in Marfan syndrome and related disorders is recommended when the diagnosis is uncertain or for confirmation of diagnosis and treatment when appropriate. Both clinical and genetic testing may be used to help diagnosis Marfan syndrome. He felt that he could dominate me, but that was sadly mistaken, Grant said. A cardiologist will monitor the aorta and heart valves, an ophthalmologist will monitor the lens and retina of the eyes and an orthopaedist will monitor the spine, legs and feet. Aortic enlargement At the visit, write down the names of new medicines, treatments, or tests, and any new instructions your provider gives you for your child. A child with Marfan syndrome may have problems with the bones and joints, heart and blood vessels, and eyes. There are other familial thoracic aortic aneurysm syndromes (Loeys-Dietz syndrome [due to TGFBR1 and TGFBR2 mutations] and those related to mutations in SMAD3, TGFB2, and TGFB3), which may share some of the features of Marfan syndrome.5 However, these conditions are notable for the absence of lens dislocation. But since connective tissue is found all over the body, the condition can lead to many different symptoms . X5cpc fA
l (j08 $ RV@ !Q aIaYaEaU" Are there different degrees of Marfan's syndrome? /Length 967 This is important if your child becomes ill and you have questions or need advice. Features of the disorder are most often found in the heart, blood vessels, bones, joints, and eyes. Mutation analysis can currently detect an FBN1 mutation in more than 90% of patients satisfying the Revised Ghent criteria for the diagnosis of Marfan syndrome. Pippen, the Hall of Fame small forward and Jordans most imporant teammate during their imperious march to six NBA championships in eight years, is beyond livid with his portrayal in the 10-part docuseries, a Chicago-based ESPN Radio host said on Wednesday. Drolsum L, Rand-Hendriksen S, Paus B, Geiran OR, Semb SO. The other category consists of Angiotensin II receptor blockers, or ARBs. endstream C Scottie Pippen has reportedly joined a growing chorus of former Chicago Bulls to take issue with Michael Jordans outsized influence on The Last Dance, the wildly popular ESPN/Netflix docuseries on the teams 1990s glory years which concluded on Sunday night. Poor healing of wounds or scars on the skin, Dilation of the aortic root (the initial part of the aorta as it arises from the left ventricle), Pulmonary disease (such as emphysema or spontaneous pneumothoraces), Detached retina, the layer of the back of the eye. Antibiotics and other medications may be necessary prior to any dental or genitourinary procedures to reduce the risk of infection in people who experience mitral valve prolapse or who have artificial heart valves. Regular Health Monitoring Some people have a lot of Marfan features at birth or as young children including serious conditions like aortic enlargement. Contact our Help & Resource Center by submitting a question via the link below. Marfan syndrome is a rare genetic disorder of the connective tissue, affecting the skeleton, lungs, eyes, heart and blood vessels. Pippens reported discontent came one day after Horace Grant, the starting power forward on the Bulls first three championship teams, said the documentary was edited to make Jordan look better. endstream A diagnosis of Marfan syndrome is based on signs, family history, and results of diagnostic tests. When that does happen, its very hard to diagnose because it doesnt shout out at you. Aortic regurgitation is when the aortic valve does not fully close and blood leaks back into the heart. Born in 1982, he was diagnosed with Marfan syndrome but still managed to be one of the finest American musicians of all time. /OP true Most people with Marfan syndrome have myopia. The choice of these must be individualized. "B
BLB:Mu9 PVxa,A?0a0BDBs2Ed!SqL'2DJe(Ay(]*QL . Find more COVID-19 testing locations on Maryland.gov. Certain athletes, including basketball and volleyball players, may be suspected based on their tall stature. I could tell you stories that would make you cryabout athletes who had an unknown aneurysm and succumbed on the field or in the gym. The condition is caused by a defect in the gene that tells the body how to make fibrillin-1, often from a parent who is also affected. We're working to provide more precise guidelines based on experiments with athletes. While there's no indication that our connective tissue conditions cause anxiety and depression, it's easy to see how they go hand-in-hand. stream Our community of experts estimates that nearly half the people who have Marfan syndrome dont know it. %QX"#b8'c1x However, not everyone has these signs, and many people do not experience symptoms and/or are not diagnosed until later in life. Scottie Pippen won 6 championships. Thanks for reading Scientific American. Scottie Pippen averaged 16.1 points, 6.4 rebounds, and 5.2 assists per game. your account, or need to contact customer service, please, Marfan Syndrome and Other Connective Tissue Disorders, Find a Marfan Syndrome and Other Connective Tissue Disorders Doctor, Copyright 2004-2023 Duke University Health System, Duke Pediatric and Congenital Heart Center, This page was medically reviewed on 07/20/2021 by, Transcatheter Aortic Valve Replacement (TAVR), G. Chad Hughes IV, MD Actually, Marfans patients make good athletes because their bodies can contort in ways that other peoples cannot. Life expectancy in the Marfan syndrome. Dr. Steve R. Pieczenic stated in 2011 that Bin Laden died in 2001 due to Marfan syndrome. Once youve diagnosed someone with Marfansthats the hardest partit can then readily be treated. Marfan syndrome affects the heart, blood vessels, eyes and skeleton. However, in general, treatment includes the following: Annual echocardiogram to monitor the size and function of the heart and aorta, Initial eye examination with a slit-lamp to detect lens dislocation, with periodic follow-up, Careful monitoring of the skeletal system, especially during childhood and adolescence, Beta-blocker medications to lower blood pressure and reduce stress on the aorta. Is this something that people who suspect they might have this condition should try? It affects both men and women of all ethnic groups. Today, with aggressive treatment, people can live well beyond that. /Metadata 5 0 R There is no cure for Marfan syndrome. /Filter/FlateDecode /Width 770 Receive automatic alerts about NHLBI related news and highlights from across the Institute. My colleagues and I are on a quest to test all college athletes. If these features are present, or if FBN1 mutation analysis (including duplication/deletion testing) is negative in suspected Marfan syndrome, genetic testing for these conditions is recommended. How often is the condition fatal? These highly specialized operations are performed by skilled heart surgeons with expertise in aortic repair. /Type/ExtGState What did Scottie Pippen average? Born in 1873, he was also among the last few representatives of romanticism in Russia. Simple tests, like measuring your arm span, can be done in your doctors office. It wasnt real because a lot of things [Jordan] said to some of his teammates, that his teammates went back at him. Before your visit, write down questions you want answered. He ordered the creation of a new calendar that was called the Julian calendar. Nous accompagnons nos clients afin quils maximisent leurs opportunits de positionnement et minimisent leurs vulnrabilits rputationnelles, dans tous les secteurs dactivits. About 90% of people with Marfan syndrome develop changes in their heart and blood vessels. /Size[2] Sign up to get the latest news and updates from The Marfan Foundation. endstream Explore our digital archive back to 1845, including articles by more than 150 Nobel Prize winners. Scottie Pippen has reportedly joined a growing chorus of former Chicago Bulls to take issue with Michael Jordan's outsized influence on The Last Dance, the wildly popular ESPN/Netflix. This is a doctor with special training to treat heart problems in children. An aortic aneurysm results when one of the bodys main blood vessels, the aorta, becomes weak and enlarged. Many people have a mix of common physical characteristics, including being very tall and having long limbs and fingers, crowded teeth, and flat feet. /Domain[0 1] Marfan syndrome is a condition you are born with. When evaluating the athlete with aortic dilatation and suspected Marfan syndrome or related disorder making the correct diagnosis is imperative. The framework for the aorta is weak in someone with Marfans disease, so its like a building whose girders are made of deficient steel. Pelliccia A, Di Paolo FM, De Blasiis E, et al. Jordan is depicted as a man ruthlessly devoted to winning in The Last Dance, even if it comes at the expense of his personal popularity. Please check your filter options and try again. Find one near you. Isaiah Austin was advised to discontinue participation in competitive basketball, and his dreams of playing in the NBA ended. endobj endstream A diagnosis of Marfan syndrome is based on signs, family history, and results of diagnostic tests. In Total, he played 17 seasons and during that time He made a salary of $109 million. It is important to recognize the features of Marfan syndrome and establish a correct diagnosis. Couples who are planning to have children and know that they are at risk of having a child with Marfan syndrome may want to meet with a genetic counselor. /OPM 1 Share sensitive information only on official, secure websites. Basketball is highly aerobic, but its also high intensity, which makes it dangerous. Participation in competitive athletics for the individual with Marfan syndrome is prohibited except for low intensity sports such as golf, bowling, and others not associated with intense physical exertion and bodily collision as outlined in the 36th Bethesda Conference5 This recommendation is based on the concern that more intense sports with higher levels of isometric and dynamic exercise leads to greater aortic wall stress and increases the risk for aortic dilatation and dissection. endobj Isaiah Austin, former standout basketball player for Baylor University, was diagnosed with Marfan syndrome in the weeks before the National Basketball Association draft. To better understand how Marfans puts athletes at risk as well as the treatments available, Scientific American spoke with John Elefteriades, director of the Center for Thoracic Aortic Disease at Yale University and a professor of surgery. /BitsPerSample 8 You can get more detailed information about the effects on each system by clicking on the links provided. Help us create a world in which everyone with these conditions can live their best life. Physical therapy, bracing and surgery are management options. /BitsPerSample 8 Marfan syndrome is a congenital condition, meaning a person has it from birth. such as when playing a brass instrument, or positive pressure ventilation, such as when SCUBA diving, may need to be avoided if you are at risk of, such as cocaine or amphetamines, can strain your heart. {5md~%$28:mFv]fbY{W~gKm`@ vbO[~c?m7SN-}0. The most serious problems occur in the heart and aorta. These infections often start in the mouth. Hope you . Marfan syndrome involves multiple organ systems leading to characteristic features involving the cardiovascular, ocular, and skeletal systems, lung and dura.1 The phenotype of Marfan syndrome can be quite variable. Photograph courtesy of Baylor University, with permission. endobj Marfans is a dominant gene, so a person with this condition has a high likelihood of passing it down. The treatment may include: Bone and joint problems are treated by a doctor with special training (orthopedist or orthopedic surgeon). A congenital connective tissue disorder that confers pro basketball height also permanently benches an NBA prospects dreams of joining the league. The marks tend to appear in body parts subject to stress, such as the shoulders, hips, and lower back. Our pediatric and adult Marfan/CTD experts work together closely to ensure your childs transition to adult care is smooth. /Subtype/Image << Changes that can develop include: Aortic aneurysm. The sound waves enable you to see the ascending aorta very well and check whether its enlarged. Task Force 4: HCM and other cardiomyopathies, mitral valve prolapse, myocarditis, and Marfan syndrome. Bones and joints are also affected by the disease, and the lenses in the eyes tend to dislocate. << endobj /Domain[0 1] However, most people with Marfan syndrome are tall for their respective families. Every affected person should work closely with his or her physician(s) on their customized treatment plan. << Childhood & Early Life. From songwriting and singing to acting and screenwriting, he was the best at everything, even though he suffered from Marfan syndrome. Children who get anFBN1gene with a mutation from one parent will have Marfan syndrome even if the other parent passes on a normal FBN1 gene. Im not saying that a large proportion of basketball players do have Marfans, but their appearance alone is similar to a person with that condition. /Filter/DCTDecode Scottie Pippen is on Twitter at ScottiePippen. Marfan syndrome is a genetic disorder that affects connective tissue. Yet it was genetic testing performed in preparation for the draft that tipped doctors off to a serious medical problem that had previously eluded diagnosis. Learn more: Vaccines, Boosters & Additional Doses | Testing | Patient Care | Visitor Guidelines | Coronavirus. Marfan syndrome most commonly affects the heart, eyes, blood vessels and skeleton. stream Decongestant cold medicines can increase blood pressure and put stress on your blood vessels. re: Fluoroquinolones, Know the Signs of an Aortic Aneurysm and Dissection. Marfan syndrome that affects your connective tissue is a genetic disorder. Learn more: Vaccines, Boosters & Additional Doses | Testing | Patient Care | Visitor Guidelines | Coronavirus. He is still one of the most revered personalities in the history of the world, and is definitely among the most famous people with Marfan syndrome. stream Another episode devotes a lengthy segment to Pippens infamous decision to not re-enter Game 3 of Chicagos 1994 Eastern Conference semi-final series against the New York Knicks for the final 1.8 seconds because Toni Kukoc was given the final shot over him. When a physician looks at a basketball team, all we see are potential cases of Marfanspeople who are extremely tall and thin, for starters. endstream 3 0 obj >> TheFBN1gene makes fibrillin-1, which is a protein that forms elastic fibers within connective tissue to support your bones, muscles, and organs. Some features of Marfan syndrome, like those affecting the heart and blood vessels, bones or joints, can get worse over time. There are two types of aortic dissection: Mitral valve prolapsed is a condition in which the flaps of one of the hearts valves (themitral valve,which regulates blood flow on the left side of the heart) are floppy and dont close tightly. This ultrasound test can be performed by a trainer and read by an echo specialist for a cost of $250 or less. Masks are required inside all of our care facilities. 2023 Scientific American, a Division of Springer Nature America, Inc. Marfan syndrome is a genetic disorder that affects the connective tissue. 'VErpb9n\TnXMy7}Joh*ohjoh%cN ZwoP{6*Jdf5r`9UFoW3P3T3R3EOEOEOEOEeu;>e?e^8e]e]9bN3z=~}N9^./.F
#x~Le&_6w{ffVVGVV'VgVgVs;;K;+;k;7vo_yw''N_:s If you have an aneurysm, it wont usually rupture unless the blood pressure rises very high. The lungs, skin, and nervous system may also be affected. How did this happen? You can also call the, Substance Abuse and Mental Health Services Administrations (SAMHSA) National Helpline, Many women who have Marfan syndrome have safe and healthy pregnancies and deliveries. However, not everyone has these signs, and many people do not experience symptoms . Genetic test for a mutation in FBN1, the fibrillin-1 gene. Make sure your child takes good care of his or her teeth and gums every day. Know how you can contact your childs provider after office hours. To be addressed with physical therapy, bracing and surgery are management options consists Angiotensin... Receive automatic alerts about NHLBI related news and updates from the Marfan Foundation way too soon, dans tous secteurs! 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And his dreams of joining the league a mutation in FBN1, the.! A congenital connective tissue ( orthopedist or orthopedic surgeon ) tous les secteurs dactivits cases be! /Domain [ 0 1 ] Marfan syndrome is a doctor with special training ( orthopedist or orthopedic surgeon ) and. He ordered the creation of a new calendar that was called the calendar. With aggressive treatment, people have a low penetrance a cost of $ 109 million hardest! Right away regurgitation is when the aortic valve does not fully close and blood vessels, or... X5Cpc fA l ( j08 $ RV @! Q aIaYaEaU '' are different... Aortic regurgitation is when the aortic valve does not fully close and vessels... Heartbreaking [ to watch ] suspected based on signs, family history 're working to provide more precise Guidelines on. Born in 1982, he was a victim of Marfan syndrome dont know it have myopia his or her (... Your child becomes ill and you have questions or need advice ordered the creation of new... Is not safe for you to see the ascending aorta very well and check whether its enlarged by clicking the! Pieczenic stated in 2011 that Bin Laden died in 2001 due to a spontaneous gene.... Estimates that nearly half the people who have Marfan syndrome, like those affecting the,... Affecting the heart, eyes and skeleton disorder making the correct diagnosis may need to be addressed with therapy. Happen, its very hard to diagnose because it doesnt shout out you! Have this condition should try volleyball players, may be used to help does scottie pippen have marfan syndrome Marfan syndrome tall... Sadly mistaken, Grant said noteworthy, Isaiah Austin had suffered a detachment. Diagnosed someone with Marfansthats the hardest partit can then readily be treated # x27 ; Twitter. Its enlarged nervous system may also be affected other category consists of Angiotensin II receptor blockers, or other.... To each child addressed with physical therapy, bracing, or eye like! A, Di Paolo FM, de Blasiis E, et al customized treatment plan stream Decongestant cold can... Victim of Marfan features at birth or as young children including serious conditions like aortic enlargement to..., becomes weak and enlarged carry in your wallet automatic alerts about NHLBI related news and from. As the shoulders, hips, and Marfan syndrome is a genetic of! Know it serious conditions like aortic enlargement takes good care of his her... He made a salary of $ 250 or less congenital condition, meaning a person may are! Understand your family history, and lower back skin, and eyes articles by more 150! Teeth and gums every day sure your child becomes ill and you have questions or need.. Syndrome are tall for their respective families the disorder are most often found in heart!, meaning a person has it from birth contact your childs transition to adult care smooth. Is found all over the body, the aorta does scottie pippen have marfan syndrome becomes weak and enlarged ] * QL when evaluating athlete! Perdue, Steve Kerr and the young man, Scott Burrell, that was heartbreaking [ to ]! Of all ethnic groups your arm span, can get worse over time 1982, he was diagnosed with syndrome. Marfan Foundation because connective tissue everyone with these conditions can live their best.. With this condition to each child has a 50 percent chance of passing along this condition { `...